Without seeing the lie it’s hard to say, but typically I would go for it. But a lie that might be a flyer for a higher lofted iron may not be for mid to long iron. At 150 to clear I’d probably hit a hard 8 or 9 iron (9i normally 150, 8i 165) but with flyer they would each fly 5-15 yds further. But that same lie with a 4-5-6 iron is more likely to fall out of the sky like a wounded duck.
But if you don’t think you have that shot, nothing wrong with laying up and trying to make par the hard way.